One-step fabrication of core–shell structured alginate–PLGA/PLLA microparticles as a novel drug delivery system for water soluble drugs

• Main Authors: Lim, Ming Pin Alan, Lee, Wei Li, Widjaja, Effendi, Loo, Say Chye Joachim
• 其他作者: School of Materials Science & Engineering
• 格式: Article
• 語言: English
• 出版: 2016
• 主題: Core shell structure; Stable encapsulation
• 在線閱讀: https://hdl.handle.net/10356/81949; http://hdl.handle.net/10220/41067
• 機構: Nanyang Technological University

Current focus on particulate drug delivery entails the need for increased drug loading and sustained release of water soluble drugs. Commonly studied biodegradable polyesters, such as poly(lactide-co-glycolide) (PLGA) and poly(L-lactide) (PLLA), are lacking in terms of loading efficiency of these dr...