Toward High-Speed Imaging of Cellular Structures in Rat Colon Using Micro-optical Coherence Tomography

• Main Authors: Yu, Xiaojun, Luo, Yuemei, Liu, Xinyu, Chen, Si, Wang, Xianghong, Chen, Shi, Liu, Linbo
• Other Authors: School of Chemical and Biomedical Engineering
• Format: Article
• Language: English
• Published: 2017
• Subjects: Optical coherence tomography; Biophotonics instrumentation
• Online Access: https://hdl.handle.net/10356/81959; http://hdl.handle.net/10220/42283
• Institution: Nanyang Technological University

The mucosal microanatomy of the large intestine is characterized by the presence of crypts of Lieberkühn, which is associated predominantly with goblet cells. Such cellular-level intestinal microstructures undergo morphological changes during the progression of bowel diseases, such as colon cancer...