Brain-derived neurotrophic factor (BDNF) Val66Met polymorphism influences the association of the methylome with maternal anxiety and neonatal brain volumes

• Main Authors: Tuan, Ta Anh, Chen, Li, Pan, Hong, Teh, Ai Ling, MacIsaac, Julia L., Mah, Sarah M., McEwen, Lisa M., Li, Yue, Chen, Helen, Broekman, Birit F. P., Buschdorf, Jan Paul, Chong, Yap Seng, Kwek, Kenneth, Saw, Seang Mei, Gluckman, Peter D., Fortier, Marielle V., Rifkin-Graboi, Anne, Kobor, Michael S., Qiu, Anqi, Meaney, Michael J., Holbrook, Joanna D.
• Other Authors: School of Biological Sciences
• Format: Article
• Language: English
• Published: 2016
• Subjects: Brain-derived neurotrophic factor (BDNF); Val66met
• Online Access: https://hdl.handle.net/10356/81986; http://hdl.handle.net/10220/41054
• Institution: Nanyang Technological University

Early life environments interact with genotype to determine stable phenotypic outcomes. Here we examined the influence of a variant in the brain-derived neurotropic factor (BDNF) gene (Val66Met), which underlies synaptic plasticity throughout the central nervous system, on the degree to which antena...