Rapid and label-free amplification and detection assay for genotyping of cancer biomarker

• Main Authors: Shin, Yong, Yoon, Jaeyun, Promoda Perera, Agampodi, Yoon, Yong-Jin, Park, Mi Kyoung, Soo, Ross A.
• Other Authors: School of Mechanical and Aerospace Engineering
• Format: Article
• Language: English
• Published: 2016
• Subjects: Silicon biophotonic sensor; Companion diagnostics
• Online Access: https://hdl.handle.net/10356/82040; http://hdl.handle.net/10220/41103
• Institution: Nanyang Technological University

As understanding of the molecular pathways that drive malignancy in human cancer improves, personalized genotype-based therapy in combination with the predictive biomarker for the efficacy of targeted therapy is becoming more popular in cancer management. Sanger sequencing, that has been the gold st...