Establishing Criteria for Human Mesenchymal Stem Cell Potency

• Main Authors: Samsonraj, Rebekah M., Rai, Bina, Sathiyanathan, Padmapriya, Puan, Kia Joo, Rötzschke, Olaf, Hui, James H., Raghunath, Michael, Stanton, Lawrence Walter, Nurcombe, Victor, Cool, Simon M.
• Other Authors: School of Biological Sciences
• Format: Article
• Language: English
• Published: 2016
• Subjects: Mesenchymal stem/stromal cells; Quality
• Online Access: https://hdl.handle.net/10356/82050; http://hdl.handle.net/10220/41091
• Institution: Nanyang Technological University

This study sought to identify critical determinants of mesenchymal stem cell (MSC) potency using in vitro and in vivo attributes of cells isolated from the bone marrow of age- and sex-matched donors. Adherence to plastic was not indicative of potency, yet capacity for long-term expansion in vitro va...