Development of a Magnetic 3D Spheroid Platform with Potential Application for High-Throughput Drug Screening

• Main Authors: Guo, Wei Mei, Loh, Xian Jun, Tan, Ern Yu, Loo, Joachim Say Chye, Ho, Vincent H. B.
• Other Authors: School of Materials Science & Engineering
• Format: Article
• Language: English
• Published: 2016
• Subjects: multicellular spheroids; magnetic cell labeling; spheroid manipulation; therapeutic studies; high-throughput screening
• Online Access: https://hdl.handle.net/10356/82058; http://hdl.handle.net/10220/39755
• Institution: Nanyang Technological University

Three-dimensional (3D) cell culture has become increasingly adopted as a more accurate model of the complex in vivo microenvironment compared to conventional two-dimensional (2D) cell culture. Multicellular spheroids are important 3D cell culture models widely used in biological studies and drug scr...