Enhanced expression of codon optimized interferon gamma in CHO cells

• Main Authors: Yusufi, Faraaz N. K., Yang, Yuansheng, Lee, Dong-Yup, Chung, Bevan Kai-Sheng, Mariati
• Other Authors: School of Chemical and Biomedical Engineering
• Format: Article
• Language: English
• Published: 2016
• Subjects: Chinese hamster ovary cells; Codon optimization
• Online Access: https://hdl.handle.net/10356/82159; http://hdl.handle.net/10220/41101
• Institution: Nanyang Technological University

The human interferon-gamma (IFN-γ) is a potential drug candidate for treating various diseases due to its immunomodulatory properties. The efficient production of this protein can be achieved through a popular industrial host, Chinese hamster ovary (CHO) cells. However, recombinant expression of for...