Crystallization and X-ray diffraction analysis of the HMG domain of the chondrogenesis master regulator Sox9 in complex with a ChIP-Seq-identified DNA element

Crystallization and X-ray diffraction analysis of the HMG domain of the chondrogenesis master regulator Sox9 in complex with a ChIP-Seq-identified DNA element

Sox9 is a fundamental sex-determining gene and the master regulator of chondrogenesis, and is involved in the development of various vital organs such as testes, kidney, heart and brain, and in skeletal development. Similar to other known Sox transcription factors, Sox9 recognizes and binds DNA with...

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Bibliographic Details
Main Authors: Vivekanandan, Saravanan, Moovarkumudalvan, Balasubramanian, Lescar, Julien, Kolatkar, Prasanna R.
Other Authors: School of Biological Sciences
Format: Article
Language:English
Published: 2016
Subjects:
Sox9
Transcription factor
Online Access:https://hdl.handle.net/10356/82165
http://hdl.handle.net/10220/41126
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Institution: Nanyang Technological University
Language: English

Internet

https://hdl.handle.net/10356/82165
http://hdl.handle.net/10220/41126

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