Molecular optical imaging probes for early diagnosis of drug-induced acute kidney injury

• Main Authors: Huang, Jiaguo, Li, Jingchao, Lyu, Yan, Miao, Qingqing, Pu, Kanyi
• Other Authors: School of Chemical and Biomedical Engineering
• Format: Article
• Language: English
• Published: 2019
• Subjects: Diagnostics; DRNTU::Engineering::Chemical engineering; Fluorescent Probes
• Online Access: https://hdl.handle.net/10356/82606; http://hdl.handle.net/10220/48884
• Institution: Nanyang Technological University

Drug-induced acute kidney injury (AKI) with a high morbidity and mortality is poorly diagnosed in hospitals and deficiently evaluated in drug discovery. Here, we report the development of molecular renal probes (MRPs) with high renal clearance efficiency for in vivo optical imaging of drug-induced A...