Fourier-based classification of protein secondary structures

The correct prediction of protein secondary structures is one of the key issues in predicting the correct protein folded shape, which is used for determining gene function. Existing methods make use of amino acids properties as indices to classify protein secondary structures, but are faced with a s...

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Main Authors: Shu, Jian-Jun, Yong, Kian Yan
Other Authors: School of Mechanical and Aerospace Engineering
Format: Article
Language:English
Published: 2017
Subjects:
Online Access:https://hdl.handle.net/10356/82620
http://hdl.handle.net/10220/42344
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Institution: Nanyang Technological University
Language: English
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spelling sg-ntu-dr.10356-826202023-03-04T17:13:27Z Fourier-based classification of protein secondary structures Shu, Jian-Jun Yong, Kian Yan School of Mechanical and Aerospace Engineering Classification Protein secondary structures The correct prediction of protein secondary structures is one of the key issues in predicting the correct protein folded shape, which is used for determining gene function. Existing methods make use of amino acids properties as indices to classify protein secondary structures, but are faced with a significant number of misclassifications. The paper presents a technique for the classification of protein secondary structures based on protein “signal-plotting” and the use of the Fourier technique for digital signal processing. New indices are proposed to classify protein secondary structures by analyzing hydrophobicity profiles. The approach is simple and straightforward. Results show that the more types of protein secondary structures can be classified by means of these newly-proposed indices. Accepted version 2017-05-05T02:59:19Z 2019-12-06T14:59:06Z 2017-05-05T02:59:19Z 2019-12-06T14:59:06Z 2017 2017 Journal Article Shu, J. -J., & Yong, K. Y. (2017). Fourier-based classification of protein secondary structures. Biochemical and Biophysical Research Communications, 485(4), 731-735. 0006-291X https://hdl.handle.net/10356/82620 http://hdl.handle.net/10220/42344 10.1016/j.bbrc.2017.02.117 196089 en Biochemical and Biophysical Research Communications © 2017 Elsevier Inc. This is the author created version of a work that has been peer reviewed and accepted for publication by Biochemical and Biophysical Research Communications, Elsevier Inc. It incorporates referee’s comments but changes resulting from the publishing process, such as copyediting, structural formatting, may not be reflected in this document. The published version is available at: [http://dx.doi.org/10.1016/j.bbrc.2017.02.117]. 9 p. application/pdf
institution Nanyang Technological University
building NTU Library
continent Asia
country Singapore
Singapore
content_provider NTU Library
collection DR-NTU
language English
topic Classification
Protein secondary structures
spellingShingle Classification
Protein secondary structures
Shu, Jian-Jun
Yong, Kian Yan
Fourier-based classification of protein secondary structures
description The correct prediction of protein secondary structures is one of the key issues in predicting the correct protein folded shape, which is used for determining gene function. Existing methods make use of amino acids properties as indices to classify protein secondary structures, but are faced with a significant number of misclassifications. The paper presents a technique for the classification of protein secondary structures based on protein “signal-plotting” and the use of the Fourier technique for digital signal processing. New indices are proposed to classify protein secondary structures by analyzing hydrophobicity profiles. The approach is simple and straightforward. Results show that the more types of protein secondary structures can be classified by means of these newly-proposed indices.
author2 School of Mechanical and Aerospace Engineering
author_facet School of Mechanical and Aerospace Engineering
Shu, Jian-Jun
Yong, Kian Yan
format Article
author Shu, Jian-Jun
Yong, Kian Yan
author_sort Shu, Jian-Jun
title Fourier-based classification of protein secondary structures
title_short Fourier-based classification of protein secondary structures
title_full Fourier-based classification of protein secondary structures
title_fullStr Fourier-based classification of protein secondary structures
title_full_unstemmed Fourier-based classification of protein secondary structures
title_sort fourier-based classification of protein secondary structures
publishDate 2017
url https://hdl.handle.net/10356/82620
http://hdl.handle.net/10220/42344
_version_ 1759858203812691968