Kinematic, Dynamic, and Energy Characteristics of Diastolic Flow in the Left Ventricle

Blood flow characteristics in the normal left ventricle are studied by using the magnetic resonance imaging, the Navier-Stokes equations, and the work-energy equation. Vortices produced during the mitral valve opening and closing are modeled in a two-dimensional analysis and correlated with temporal...

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Main Authors: Khalafvand, Seyed Saeid, Hung, Tin-Kan, Ng, Eddie Yin-Kwee, Zhong, Liang
Other Authors: School of Mechanical and Aerospace Engineering
Format: Article
Language:English
Published: 2016
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Online Access:https://hdl.handle.net/10356/82830
http://hdl.handle.net/10220/40348
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Institution: Nanyang Technological University
Language: English
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spelling sg-ntu-dr.10356-828302023-03-04T17:14:11Z Kinematic, Dynamic, and Energy Characteristics of Diastolic Flow in the Left Ventricle Khalafvand, Seyed Saeid Hung, Tin-Kan Ng, Eddie Yin-Kwee Zhong, Liang School of Mechanical and Aerospace Engineering mitral valve blood flow Blood flow characteristics in the normal left ventricle are studied by using the magnetic resonance imaging, the Navier-Stokes equations, and the work-energy equation. Vortices produced during the mitral valve opening and closing are modeled in a two-dimensional analysis and correlated with temporal variations of the Reynolds number and pressure drop. Low shear stress and net pressures on the mitral valve are obtained for flow acceleration and deceleration. Bernoulli energy flux delivered to blood from ventricular dilation is practically balanced by the energy influx and the rate change of kinetic energy in the ventricle. The rates of work done by shear and energy dissipation are small. The dynamic and energy characteristics of the 2D results are comparable to those of a 3D model. MOH (Min. of Health, S’pore) Published version 2016-03-30T08:46:57Z 2019-12-06T15:06:28Z 2016-03-30T08:46:57Z 2019-12-06T15:06:28Z 2015 Journal Article Khalafvand, S. S., Hung, T. K., Ng, E. Y.-K., & Zhong, L. (2015). Kinematic, Dynamic, and Energy Characteristics of Diastolic Flow in the Left Ventricle. Computational and Mathematical Methods in Medicine, 2015, 701945-. 1748-670X https://hdl.handle.net/10356/82830 http://hdl.handle.net/10220/40348 10.1155/2015/701945 26417381 en Computational and Mathematical Methods in Medicine © 2015 Seyed Saeid Khalafvand et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. 13 p. application/pdf
institution Nanyang Technological University
building NTU Library
continent Asia
country Singapore
Singapore
content_provider NTU Library
collection DR-NTU
language English
topic mitral valve
blood flow
spellingShingle mitral valve
blood flow
Khalafvand, Seyed Saeid
Hung, Tin-Kan
Ng, Eddie Yin-Kwee
Zhong, Liang
Kinematic, Dynamic, and Energy Characteristics of Diastolic Flow in the Left Ventricle
description Blood flow characteristics in the normal left ventricle are studied by using the magnetic resonance imaging, the Navier-Stokes equations, and the work-energy equation. Vortices produced during the mitral valve opening and closing are modeled in a two-dimensional analysis and correlated with temporal variations of the Reynolds number and pressure drop. Low shear stress and net pressures on the mitral valve are obtained for flow acceleration and deceleration. Bernoulli energy flux delivered to blood from ventricular dilation is practically balanced by the energy influx and the rate change of kinetic energy in the ventricle. The rates of work done by shear and energy dissipation are small. The dynamic and energy characteristics of the 2D results are comparable to those of a 3D model.
author2 School of Mechanical and Aerospace Engineering
author_facet School of Mechanical and Aerospace Engineering
Khalafvand, Seyed Saeid
Hung, Tin-Kan
Ng, Eddie Yin-Kwee
Zhong, Liang
format Article
author Khalafvand, Seyed Saeid
Hung, Tin-Kan
Ng, Eddie Yin-Kwee
Zhong, Liang
author_sort Khalafvand, Seyed Saeid
title Kinematic, Dynamic, and Energy Characteristics of Diastolic Flow in the Left Ventricle
title_short Kinematic, Dynamic, and Energy Characteristics of Diastolic Flow in the Left Ventricle
title_full Kinematic, Dynamic, and Energy Characteristics of Diastolic Flow in the Left Ventricle
title_fullStr Kinematic, Dynamic, and Energy Characteristics of Diastolic Flow in the Left Ventricle
title_full_unstemmed Kinematic, Dynamic, and Energy Characteristics of Diastolic Flow in the Left Ventricle
title_sort kinematic, dynamic, and energy characteristics of diastolic flow in the left ventricle
publishDate 2016
url https://hdl.handle.net/10356/82830
http://hdl.handle.net/10220/40348
_version_ 1759857478388940800