Chitinase activation in patients with fungus-associated cystic fibrosis lung disease

• Main Authors: Hector, Andreas, Chotirmall, Sanjay Haresh, Lavelle, Gillian M., Mirković, Bojana, Horan, Deirdre, Eichler, Laura, Mezger, Markus, Singh, Anurag, Ralhan, Anjai, Berenbrinker, Sina, Mack, Ines, Ensenauer, Regina, Riethmüller, Joachim, Graepler-Mainka, Ute, Murray, Michelle A., Griese, Matthias, Gerry McElvaney, N., Hartl, Dominik
• Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
• Format: Article
• Language: English
• Published: 2017
• Subjects: Cystic fibrosis; Lung disease
• Online Access: https://hdl.handle.net/10356/83011; http://hdl.handle.net/10220/42386
• Institution: Nanyang Technological University

BACKGROUND: Chitinases have recently gained attention in the field of pulmonary diseases, particularly in asthma and chronic obstructive pulmonary disease, but their potential role in patients with cystic fibrosis (CF)-associated lung disease remains unclear. OBJECTIVE: The aim of this study was to...