Modeling of Mechanical Stress Exerted by Cholesterol Crystallization on Atherosclerotic Plaques

• Main Authors: Luo, Yuemei, Cui, Dongyao, Yu, Xiaojun, Chen, Si, Liu, Xinyu, Tang, Hongying, Wang, Xianghong, Liu, Linbo
• Other Authors: Feng, Ying-Mei
• Format: Article
• Language: English
• Published: 2017
• Subjects: Cholesterol Crystallization; Atherosclerotic Plaques
• Online Access: https://hdl.handle.net/10356/83119; http://hdl.handle.net/10220/42415
• Institution: Nanyang Technological University

Plaque rupture is the critical cause of cardiovascular thrombosis, but the detailed mechanisms are not fully understood. Recent studies have found abundant cholesterol crystals in ruptured plaques, and it has been proposed that the rapid expansion of cholesterol crystals in a limited space during cr...