Protein delivery options: how well have we succeeded?

• Main Authors: Ng, Xu Wen, Subbu, Venkatraman
• Other Authors: School of Materials Science & Engineering
• Format: Article
• Language: English
• Published: 2017
• Subjects: Protein; Recombinant Antibodies
• Online Access: https://hdl.handle.net/10356/83239; http://hdl.handle.net/10220/42495
• Institution: Nanyang Technological University

Of the ten top-selling drugs in 2013, the first three (Humira®, Enbrel®, Remicade®) were all monoclonal antibodies for treating autoimmune diseases; together these three accounted for approximately $28 billion in sales. Another antibody, Avastin®, indicated for bowel cancer, accounted for $6.7 billi...