Modulating Antimicrobial Activity and Mammalian Cell Biocompatibility with Glucosamine-Functionalized Star Polymers

• Main Authors: Wong, Edgar H. H., Khin, Mya Mya, Ravikumar, Vikashini, Si, Zhangyong, Rice, Scott A., Chan-Park, Mary B.
• Other Authors: School of Chemical and Biomedical Engineering
• Format: Article
• Language: English
• Published: 2016
• Subjects: Mammalian cell; Biomacromolecules
• Online Access: https://hdl.handle.net/10356/83400; http://hdl.handle.net/10220/41424
• Institution: Nanyang Technological University

The development of novel reagents and antibiotics for combating multidrug resistance bacteria has received significant attention in recent years. In this study, new antimicrobial star polymers (14–26 nm in diameter) that consist of mixtures of polylysine and glycopolymer arms were developed and were...