Fusaric acid and analogues as Gram-negative bacterial quorum sensing inhibitors

• المؤلفون الرئيسيون: Tung, Truong Thanh, Jakobsen, Tim Holm, Dao, Trong Tuan, Fuglsang, Anja Thoe, Givskov, Michael, Christensen, Søren Brøgger, Nielsen, John
• مؤلفون آخرون: Singapore Centre for Environmental Life Sciences Engineering
• التنسيق: مقال
• اللغة: English
• منشور في: 2017
• الموضوعات: Quorum sensing inhibitors; Fusaric acid
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/83479; http://hdl.handle.net/10220/42594
• المؤسسة: Nanyang Technological University

Taking advantage of microwave-assisted synthesis, efficient and expedite procedures for preparation of a library of fusaric acid and 39 analogues are reported. The fusaric acid analogues were tested in cell-based screening assays for inhibition of the las and rhl quorum sensing system in Pseudomonas...