Fusaric acid and analogues as Gram-negative bacterial quorum sensing inhibitors
Taking advantage of microwave-assisted synthesis, efficient and expedite procedures for preparation of a library of fusaric acid and 39 analogues are reported. The fusaric acid analogues were tested in cell-based screening assays for inhibition of the las and rhl quorum sensing system in Pseudomonas...
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Main Authors: | Tung, Truong Thanh, Jakobsen, Tim Holm, Dao, Trong Tuan, Fuglsang, Anja Thoe, Givskov, Michael, Christensen, Søren Brøgger, Nielsen, John |
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Other Authors: | Singapore Centre for Environmental Life Sciences Engineering |
Format: | Article |
Language: | English |
Published: |
2017
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Subjects: | |
Online Access: | https://hdl.handle.net/10356/83479 http://hdl.handle.net/10220/42594 |
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Institution: | Nanyang Technological University |
Language: | English |
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