Roles of computational modelling in understanding p53 structure, biology, and its therapeutic targeting

The transcription factor p53 plays pivotal roles in numerous biological processes, including the suppression of tumours. The rich availability of biophysical data aimed at understanding its structure–function relationships since the 1990s has enabled the application of a variety of computational mod...

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Bibliographic Details
Main Authors: Tan, Yaw Sing, Mhoumadi, Yasmina, Verma, Chandra Shekhar
Other Authors: Lane, David P
Format: Article
Language:English
Published: 2019
Subjects:
p53
Online Access:https://hdl.handle.net/10356/83525
http://hdl.handle.net/10220/49762
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Institution: Nanyang Technological University
Language: English