Tryptophan end-tagging for promoted lipopolysaccharide interactions and anti-inflammatory effects

• Main Authors: Singh, Shalini, Datta, Aritreyee, Schmidtchen, Artur, Bhunia, Anirban, Malmsten, Martin
• Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
• Format: Article
• Language: English
• Published: 2017
• Subjects: Anti-inflammatory effects; Tryptophan end-tagging
• Online Access: https://hdl.handle.net/10356/83612; http://hdl.handle.net/10220/42712
• Institution: Nanyang Technological University

The objective of the present study is the investigation of possibilities for boosting peptide anti-inflammatory effects by tryptophan end-tagging, including identification of underlying mechanisms for this. In doing so, effects of tryptophan end-tagging of KYE21 (KYEITTIHNLFRKLTHRLFRR), a peptide de...