Membrane Active Antimicrobial Peptides: Translating Mechanistic Insights to Design

• Main Authors: Li, Jianguo, Koh, Jun-Jie, Liu, Shouping, Lakshminarayanan, Rajamani, Verma, Chandra Shekhar, Beuerman, Roger W.
• Other Authors: School of Biological Sciences
• Format: Article
• Language: English
• Published: 2017
• Subjects: Antimicrobial peptides; Action mechanism
• Online Access: https://hdl.handle.net/10356/83613; http://hdl.handle.net/10220/42720
• Institution: Nanyang Technological University

Antimicrobial peptides (AMPs) are promising next generation antibiotics that hold great potential for combating bacterial resistance. AMPs can be both bacteriostatic and bactericidal, induce rapid killing and display a lower propensity to develop resistance than do conventional antibiotics. Despite...