Automatic Detection of Endothelial Cells in 3D Angiogenic Sprouts from Experimental Phase Contrast Images

• Main Authors: Wang, MengMeng, Ong, Lee-Ling Sharon, Dauwels, Justin, Asada, H. Harry
• Other Authors: Ourselin, Sébastien
• Format: Article
• Language: English
• Published: 2015
• Subjects: Endothelial cell detection; 3D angiogenic sprouts; partial least square regression; phase contrast images
• Online Access: https://hdl.handle.net/10356/83651; http://hdl.handle.net/10220/39157
• Institution: Nanyang Technological University

Cell migration studies in 3D environments become more popular, as cell behaviors in 3D are more similar to the behaviors of cells in a living organism (in vivo). We focus on the 3D angiogenic sprouting in microfluidic devices, where Endothelial Cells (ECs) burrow into the gel matrix and form solid l...