Genetics and Genomics of Longitudinal Lung Function Patterns in Individuals with Asthma

• Main Authors: Yates, Katherine P., McGeachie, Michael J., Zhou, Xiaobo, Guo, Feng, Sternberg, Alice L., Van Natta, Mark L., Wise, Robert A., Szefler, Stanley J., Sharma, Sunita, Kho, Alvin T., Cho, Michael H., Croteau-Chonka, Damien C., Castaldi, Peter J., Jain, Gaurav, Sanyal, Amartya, Zhan, Ye, Lajoie, Bryan R., Dekker, Job, Stamatoyannopoulos, John, Covar, Ronina A., Zeiger, Robert S., Adkinson, N. Franklin, Williams, Paul V., Kelly, H. William, Grasemann, Hartmut, Vonk, Judith M., Koppelman, Gerard H., Postma, Dirkje S., Raby, Benjamin A., Houston, Isaac, Lu, Quan, Fuhlbrigge, Anne L., Tantisira, Kelan G., Silverman, Edwin K., Tonascia, James, Strunk, Robert C., Weiss, Scott T.
• Other Authors: School of Biological Sciences
• Format: Article
• Language: English
• Published: 2017
• Subjects: CSMD3; Asthma
• Online Access: https://hdl.handle.net/10356/83722; http://hdl.handle.net/10220/42799
• Institution: Nanyang Technological University

Rationale: Patterns of longitudinal lung function growth and decline in childhood asthma have been shown to be important in determining risk for future respiratory ailments including chronic airway obstruction and chronic obstructive pulmonary disease. Objectives: To determine the genetic underpinni...