Ablating the aryl hydrocarbon receptor (AhR) in CD11c+ cells perturbs intestinal epithelium development and intestinal immunity

Ablating the aryl hydrocarbon receptor (AhR) in CD11c+ cells perturbs intestinal epithelium development and intestinal immunity

Diet and microbiome derived indole derivatives are known to activate the ligand induced transcription factor, the Aryl hydrocarbon Receptor (AhR). While the current understanding of AhR biology has confirmed its role in mucosal lymphocytes, its function in intestinal antigen presenting cells (APCs)...

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Bibliographic Details
Main Authors: Chng, Song Hui, Kundu, Parag, Dominguez-Brauer, Carmen, Teo, Wei Ling, Mak, Tak Wah, Pettersson, Sven, Kawajiri, Kaname, Fujii-Kuriyama, Yoshiaki
Other Authors: School of Biological Sciences
Format: Article
Language:English
Published: 2016
Subjects:
Innate immunity
Mucosal immunology
Online Access:https://hdl.handle.net/10356/83806
http://hdl.handle.net/10220/41461
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Institution: Nanyang Technological University
Language: English

Internet

https://hdl.handle.net/10356/83806
http://hdl.handle.net/10220/41461

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