A biodegradable ocular implant for long-term suppression of intraocular pressure

• المؤلفون الرئيسيون: Ng, Xu Wen, Liu, Kerh Lin, Veluchamy, Amutha Barathi, Lwin, Nyein Chan, Wong, Tina T., Venkatraman, Subbu Subramanian
• مؤلفون آخرون: School of Materials Science & Engineering
• التنسيق: مقال
• اللغة: English
• منشور في: 2016
• الموضوعات: Biodegradable; Polymer
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/83816; http://hdl.handle.net/10220/41450
• المؤسسة: Nanyang Technological University

Timolol maleate (TM) has been used for many years for the reduction of intraocular pressure (IOP) in glaucoma patients. However, the topical mode of administration (eyedrops) is far from optimal because of the issues of low bioavailability, high drug wastage, and lack of patient compliance. Suboptim...