A biodegradable ocular implant for long-term suppression of intraocular pressure

• Main Authors: Ng, Xu Wen, Liu, Kerh Lin, Veluchamy, Amutha Barathi, Lwin, Nyein Chan, Wong, Tina T., Venkatraman, Subbu Subramanian
• Other Authors: School of Materials Science & Engineering
• Format: Article
• Language: English
• Published: 2016
• Subjects: Biodegradable; Polymer
• Online Access: https://hdl.handle.net/10356/83816; http://hdl.handle.net/10220/41450
• Institution: Nanyang Technological University

Timolol maleate (TM) has been used for many years for the reduction of intraocular pressure (IOP) in glaucoma patients. However, the topical mode of administration (eyedrops) is far from optimal because of the issues of low bioavailability, high drug wastage, and lack of patient compliance. Suboptim...