Improving Microbial Biogasoline Production in Escherichia coli Using Tolerance Engineering

• Main Authors: Foo, Jee Loon, Jensen, Heather M., Dahl, Robert H., George, Kevin, Keasling, Jay D., Lee, Taek Soon, Leong, Susanna, Mukhopadhyay, Aindrila
• Other Authors: School of Chemical and Biomedical Engineering
• Format: Article
• Language: English
• Published: 2016
• Subjects: isopentenol; biosynthesis
• Online Access: https://hdl.handle.net/10356/83857; http://hdl.handle.net/10220/40040
• Institution: Nanyang Technological University

Engineering microbial hosts for the production of fungible fuels requires mitigation of limitations posed on the production capacity. One such limitation arises from the inherent toxicity of solvent-like biofuel compounds to production strains, such as Escherichia coli. Here we show the importance o...