High expression of MnSOD promotes survival of circulating breast cancer cells and increases their resistance to doxorubicin

• Main Authors: Fu, Afu, Ma, Shijun, Wei, Na, Tan, Blanche Xiao Xuan, Tan, Ern Yu, Luo, Kathy Qian
• Other Authors: School of Chemical and Biomedical Engineering
• Format: Article
• Language: English
• Published: 2017
• Subjects: Breast cancer metastasis; MnSOD
• Online Access: https://hdl.handle.net/10356/84055; http://hdl.handle.net/10220/42932
• Institution: Nanyang Technological University

Understanding the survival mechanism of metastatic cancer cells in circulation will provide new perspectives on metastasis prevention and also shed new light on metastasis-derived drug resistance. In this study, we made it feasible to detect apoptosis of circulating tumor cells (CTCs) in real-time b...