Dry Powder Printing Technology: A Possible Dosing Approach for Solid Dosage Forms of Personalized Medicine

A traditional medicationis generally designed for a heterogeneous population of patients admitted with a same or similar symptom. The main disadvantages of such traditional drug products, are the single disease treatment and the fixed dose that make it not suitable to specific groups of patients, su...

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Bibliographic Details
Main Authors: Li, Zongqi, Yang, Shoufeng
Other Authors: Proceedings of the 1st International Conference on Progress in Additive Manufacturing (Pro-AM 2014)
Format: Conference or Workshop Item
Language:English
Published: 2016
Subjects:
Online Access:https://hdl.handle.net/10356/84211
http://hdl.handle.net/10220/41693
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Institution: Nanyang Technological University
Language: English
Description
Summary:A traditional medicationis generally designed for a heterogeneous population of patients admitted with a same or similar symptom. The main disadvantages of such traditional drug products, are the single disease treatment and the fixed dose that make it not suitable to specific groups of patients, such as children, the aged and drug-susceptible patients. Personalized medicine, as a technological advancement, can promise all prediction, prevention and treatment of disease that are targeted to individual patients’ need. Solid dosage forms, popular due to their advantages comparing with liquid forms, were produced by a new dosing approach using a dry powder drop-on-demand printing technology. Capsule filling with inhalation grade lactose demonstrated the potential of this technology to be applied in the production of personalized medicine.