Stochastic simulation of HIV population dynamics through complex network modelling

We propose a new way to model HIV infection spreading through the use of dynamic complex networks. The heterogeneous population of HIV exposure groups is described through a unique network degree probability distribution. The time evolution of the network nodes is modelled by a Markov process and gi...

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Bibliographic Details
Main Authors: Sloot, Peter M. A., Ivanov, S. V., Boukhanovsky, Alexander V., Boucher, Charles A. B., van de Vijver, David A. M. C.
Other Authors: School of Computer Engineering
Format: Article
Language:English
Published: 2013
Online Access:https://hdl.handle.net/10356/84333
http://hdl.handle.net/10220/10126
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Institution: Nanyang Technological University
Language: English
Description
Summary:We propose a new way to model HIV infection spreading through the use of dynamic complex networks. The heterogeneous population of HIV exposure groups is described through a unique network degree probability distribution. The time evolution of the network nodes is modelled by a Markov process and gives insight in HIV disease progression. The results are validated against historical data of AIDS cases in the USA as recorded by the Center of Disease Control. We find a remarkably good correspondence between the number of simulated and registered HIV cases, indicating that our approach to modelling the dynamics of HIV spreading through a sexual network is a valid approach that opens up completely new ways of reasoning about various medication scenarios.