Intestinal PPARγ signalling is required for sympathetic nervous system activation in response to caloric restriction

• Main Authors: Duszka, Kalina, Picard, Alexandre, Ellero-Simatos, Sandrine, Chen, Jiapeng, Defernez, Marianne, Paramalingam, Eeswari, Pigram, Anna, Vanoaica, Liviu, Canlet, Cécile, Parini, Paolo, Narbad, Arjan, Guillou, Hervé, Thorens, Bernard, Wahli, Walter
• Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
• Format: Article
• Language: English
• Published: 2016
• Subjects: Gene expression; Metabolomics
• Online Access: https://hdl.handle.net/10356/84346; http://hdl.handle.net/10220/41789
• Institution: Nanyang Technological University

Nuclear receptor PPARγ has been proven to affect metabolism in multiple tissues, and has received considerable attention for its involvement in colon cancer and inflammatory disease. However, its role in intestinal metabolism has been largely ignored. To investigate this potential aspect of PPARγ fu...