Irradiation of Epithelial Carcinoma Cells Upregulates Calcium-Binding Proteins That Promote Survival under Hypoxic Conditions

• المؤلفون الرئيسيون: Ren, Yan, Yeoh, Kheng Wei, Hao, Piliang, Kon, Oi Lian, Sze, Siu Kwan
• مؤلفون آخرون: School of Biological Sciences
• التنسيق: مقال
• اللغة: English
• منشور في: 2016
• الموضوعات: Cancer; Calcium signaling
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/84713; http://hdl.handle.net/10220/41920

Hypoxia is thought to promote tumor radio-resistance via effects on gene expression in cancer cells that modulate their metabolism, proliferation, and DNA repair pathways to enhance survival. Here we demonstrate for the first time that under hypoxic condition A431 epithelial carcinoma cells exhibit...