Effect of time discretization on the limit of the accuracy of parameter estimation for moving single molecules imaged by fluorescence microscopy

• Main Authors: Lin, Zhiping, Wong, Yau., Ober, Raimund J.
• Other Authors: School of Electrical and Electronic Engineering
• Format: Conference or Workshop Item
• Language: English
• Published: 2013
• Online Access: https://hdl.handle.net/10356/84776; http://hdl.handle.net/10220/12806
• Institution: Nanyang Technological University

In this paper, we consider the problem of the accuracy of estimating the location and other attributes of a moving single molecule whose trajectory is acquired in a sequence of time intervals by a pixelated detector. We present expressions of the Fisher information matrices from which the benchmark...