Identification of a Novel Parallel β-Strand Conformation within Molecular Monolayer of Amyloid Peptide

• Main Authors: Liu, Lei, Li, Qiang, Zhang, Shuai, Wang, Xiaofeng, Hoffmann, Søren Vrønning, Li, Jingyuan, Liu, Zheng, Besenbacher, Flemming, Dong, Mingdong
• 其他作者: School of Materials Science & Engineering
• 格式: Article
• 語言: English
• 出版: 2017
• 主題: Atomic force microscopy; Amyloid peptide aggregation
• 在線閱讀: https://hdl.handle.net/10356/85006; http://hdl.handle.net/10220/42054
• 機構: Nanyang Technological University

The differentiation of protein properties and biological functions arises from the variation in the primary and secondary structure. Specifically, in abnormal assemblies of protein, such as amyloid peptide, the secondary structure is closely correlated with the stable ensemble and the cytotoxicity....