Fabrication of titanium based biphasic scaffold using selective laser melting and collagen immersion
Tissue engineering approaches have been adopted to address challenges in osteochondral tissue regeneration. Single phase scaffolds, which consist of only one single material throughout the whole structure, have been used extensively in these tissue engineering approaches. However, a single phase sca...
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sg-ntu-dr.10356-850462020-09-26T22:07:11Z Fabrication of titanium based biphasic scaffold using selective laser melting and collagen immersion Sing, Swee Leong Wang, Shuai Agarwala, Shweta Wiria, Florencia Edith Ha, Thi Mai Hoa Yeong, Wai Yee School of Mechanical and Aerospace Engineering A*STAR SIMTech Singapore Centre for 3D Printing Selective Laser Melting Titanium Tissue engineering approaches have been adopted to address challenges in osteochondral tissue regeneration. Single phase scaffolds, which consist of only one single material throughout the whole structure, have been used extensively in these tissue engineering approaches. However, a single phase scaffold is insufficient in providing all the properties required for regeneration and repair of osteochondral defects. Biphasic scaffolds with two distinct phases of titanium/type 1 collagen and titanium-tantalum/type 1 collagen were developed for the first time using selective laser melting. Observation of the biphasic scaffolds demonstrated continuous interface between the two phases and mechanical characterization of the metallic scaffolds support the feasibility of the newly developed scaffolds for tissue engineering in osteochondral defects. Published version 2018-03-02T08:13:24Z 2019-12-06T15:56:08Z 2018-03-02T08:13:24Z 2019-12-06T15:56:08Z 2017 2017 Journal Article Sing, S. L., Wang, S., Agarwala, S., Wiria, F. E., Ha, T. M. H., & Yeong, W. Y. (2017). Fabrication of titanium based biphasic scaffold using selective laser melting and collagen immersion. International Journal of Bioprinting, 3(1), 65-71. https://hdl.handle.net/10356/85046 http://hdl.handle.net/10220/44488 10.18063/IJB.2017.01.007 196052 en International Journal of Bioprinting © 2017 Swee Leong Sing, et al. This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), permitting all non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. 7 p. application/pdf |
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Selective Laser Melting Titanium |
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Selective Laser Melting Titanium Sing, Swee Leong Wang, Shuai Agarwala, Shweta Wiria, Florencia Edith Ha, Thi Mai Hoa Yeong, Wai Yee Fabrication of titanium based biphasic scaffold using selective laser melting and collagen immersion |
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Tissue engineering approaches have been adopted to address challenges in osteochondral tissue regeneration. Single phase scaffolds, which consist of only one single material throughout the whole structure, have been used extensively in these tissue engineering approaches. However, a single phase scaffold is insufficient in providing all the properties required for regeneration and repair of osteochondral defects. Biphasic scaffolds with two distinct phases of titanium/type 1 collagen and titanium-tantalum/type 1 collagen were developed for the first time using selective laser melting. Observation of the biphasic scaffolds demonstrated continuous interface between the two phases and mechanical characterization of the metallic scaffolds support the feasibility of the newly developed scaffolds for tissue engineering in osteochondral defects. |
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School of Mechanical and Aerospace Engineering |
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School of Mechanical and Aerospace Engineering Sing, Swee Leong Wang, Shuai Agarwala, Shweta Wiria, Florencia Edith Ha, Thi Mai Hoa Yeong, Wai Yee |
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Article |
author |
Sing, Swee Leong Wang, Shuai Agarwala, Shweta Wiria, Florencia Edith Ha, Thi Mai Hoa Yeong, Wai Yee |
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Sing, Swee Leong |
title |
Fabrication of titanium based biphasic scaffold using selective laser melting and collagen immersion |
title_short |
Fabrication of titanium based biphasic scaffold using selective laser melting and collagen immersion |
title_full |
Fabrication of titanium based biphasic scaffold using selective laser melting and collagen immersion |
title_fullStr |
Fabrication of titanium based biphasic scaffold using selective laser melting and collagen immersion |
title_full_unstemmed |
Fabrication of titanium based biphasic scaffold using selective laser melting and collagen immersion |
title_sort |
fabrication of titanium based biphasic scaffold using selective laser melting and collagen immersion |
publishDate |
2018 |
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https://hdl.handle.net/10356/85046 http://hdl.handle.net/10220/44488 |
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