Aurora kinase-induced phosphorylation excludes transcription factor RUNX from the chromatin to facilitate proper mitotic progression

Aurora kinase-induced phosphorylation excludes transcription factor RUNX from the chromatin to facilitate proper mitotic progression

The Runt-related transcription factors (RUNX) are master regulators of development and major players in tumorigenesis. Interestingly, unlike most transcription factors, RUNX proteins are detected on the mitotic chromatin and apparatus, suggesting that they are functionally active in mitosis. Here, w...

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Bibliographic Details
Main Authors: Chuang, Linda Shyue Huey, Khor, Jian Ming, Lai, Soak Kuan, Garg, Shubham, Krishnan, Vaidehi, Koh, Cheng-Gee, Lee, Sang Hyun, Ito, Yoshiaki
Other Authors: School of Biological Sciences
Format: Article
Language:English
Published: 2017
Subjects:
RUNX
Phosphorylation
Online Access:https://hdl.handle.net/10356/85151
http://hdl.handle.net/10220/43655
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Institution: Nanyang Technological University
Language: English

Internet

https://hdl.handle.net/10356/85151
http://hdl.handle.net/10220/43655

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