Mechanical strain alters cellular and nuclear dynamics at early stages of oligodendrocyte differentiation

• المؤلفون الرئيسيون: Makhija, Ekta, Jagielska, Anna, Zhu, Lena, Bost, Alexander C., Ong, William, Shivashankar, G. V., Van Vliet, Krystyn J., Chew, Sing Yian
• مؤلفون آخرون: Interdisciplinary Graduate School (IGS)
• التنسيق: مقال
• اللغة: English
• منشور في: 2018
• الموضوعات: Oligodendrocyte Differentiation; Strain
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/85192; http://hdl.handle.net/10220/45095

Mechanical and physical stimuli including material stiffness and topography or applied mechanical strain have been demonstrated to modulate differentiation of glial progenitor and neural stem cells. Recent studies probing such mechanotransduction in oligodendrocytes have focused chiefly on the biomo...