Hybrid microscaffold-based 3D bioprinting of multi-cellular constructs with high compressive strength : a new biofabrication strategy

• Main Authors: Tan, Yu Jun, Tan, Xipeng, Yeong, Wai Yee, Tor, Shu Beng
• Other Authors: School of Mechanical and Aerospace Engineering
• Format: Article
• Language: English
• Published: 2018
• Subjects: Tissue Scaffolds; Bioprinting; DRNTU::Engineering::Mechanical engineering
• Online Access: https://hdl.handle.net/10356/85428; http://hdl.handle.net/10220/46677
• Institution: Nanyang Technological University

A hybrid 3D bioprinting approach using porous microscaffolds and extrusion-based printing method is presented. Bioink constitutes of cell-laden poly(D,L-lactic-co-glycolic acid) (PLGA) porous microspheres with thin encapsulation of agarose-collagen composite hydrogel (AC hydrogel). Highly porous mic...