Similarity and diversity of translational GTPase factors EF-G, EF4, and BipA: From structure to function

• Main Authors: Ero, Rya, Kumar, Veerendra, Chen, Yun, Gao, Yong-Gui
• Other Authors: School of Biological Sciences
• Format: Article
• Language: English
• Published: 2017
• Subjects: BipA; EF-G
• Online Access: https://hdl.handle.net/10356/85549; http://hdl.handle.net/10220/43733
• Institution: Nanyang Technological University

EF-G, EF4, and BipA are members of the translation factor family of GTPases with a common ribosome binding mode and GTPase activation mechanism. However, topological variations of shared as well as unique domains ensure different roles played by these proteins during translation. Recent X-ray crysta...