A facile method for fabricating a three-dimensional aligned fibrous scaffold for vascular application

• Main Authors: Ng, Feng Lin, Ong, Yee Oon, Chen, Hui Zhi, Tran, Le Quan Ngoc, Cao, Ye, Tay, Bee Yen, Tan, Lay Poh
• Other Authors: School of Materials Science and Engineering
• Format: Article
• Language: English
• Published: 2019
• Subjects: Engineering::Materials; Vascular Graft; Fibres
• Online Access: https://hdl.handle.net/10356/85635; http://hdl.handle.net/10220/49830
• Institution: Nanyang Technological University

Vascular graft replacement remains the optimal treatment option for many vascular diseases despite advances in endovascular surgery. In this study, we proposed the use of surface topographical cues to align and maintain the phenotype of vascular smooth muscle cells (vSMCs) which were reported as one...