Highly selective transmission success of dengue virus type 1 lineages in a dynamic virus population : an evolutionary and fitness perspective

• Main Authors: Koo, Carmen, Tien, Wei Ping, Xu, Helen, Ong, Janet, Rajarethinam, Jayanthi, Lai, Yee Ling, Ng, Lee-Ching, Hapuarachchi, Hapuarachchige Chanditha
• Other Authors: School of Biological Sciences
• Format: Article
• Language: English
• Published: 2019
• Subjects: Disease; Virology; Science::Biological sciences
• Online Access: https://hdl.handle.net/10356/85711; http://hdl.handle.net/10220/49841
• Institution: Nanyang Technological University

Arbovirus transmission is modulated by host, vector, virus, and environmental factors. Even though viral fitness plays a salient role in host and vector adaptation, the transmission success of individual strains in a heterogeneous population may be stochastic. Our large-scale molecular epidemiologic...