NetLand: quantitative modeling and visualization of Waddington’s epigenetic landscape using probabilistic potential

• Main Authors: Guo, Jing, Lin, Feng, Zhang, Xiaomeng, Tanavde, Vivek, Zheng, Jie
• Other Authors: School of Computer Science and Engineering
• Format: Article
• Language: English
• Published: 2017
• Online Access: https://hdl.handle.net/10356/85842; http://hdl.handle.net/10220/43851; https://doi.org/10.21979/N9/IP6DBD
• Institution: Nanyang Technological University

Summary: Waddington’s epigenetic landscape is a powerful metaphor for cellular dynamics driven by gene regulatory networks (GRNs). Its quantitative modeling and visualization, however, remains a challenge, especially when there are more than two genes in the network. A software tool for Waddington’s...