Differential epithelial and stromal protein profiles in cone and non-cone regions of keratoconus corneas

• Main Authors: Yam, Gary Hin-Fai, Fuest, Matthias, Zhou, Lei, Liu, Yu-Chi, Deng, Lu, Chan, Anita Sook-Yee, Ong, Hon Shing, Khor, Wei-Boon, Ang, Marcus, Mehta, Jodhbir Singh
• Other Authors: School of Materials Science & Engineering
• Format: Article
• Language: English
• Published: 2019
• Subjects: DRNTU::Engineering::Materials; Proteome Informatics; Corneal Diseases
• Online Access: https://hdl.handle.net/10356/85860; http://hdl.handle.net/10220/48250
• Institution: Nanyang Technological University

Keratoconus (KC) is an ectatic corneal disease characterized by progressive thinning and irregular astigmatism, and a leading indication for corneal transplantation. KC-associated changes have been demonstrated for the entire cornea, but the pathological thinning and mechanical weakening is usually...