Quantum dots-siRNA nanoplexes for gene silencing in central nervous system tumor cells

• Main Authors: Lin, Guimiao, Chen, Ting, Zou, Jinyun, Wang, Yucheng, Wang, Xiaomei, Li, Jiefeng, Huang, Qijun, Fu, Zicai, Zhao, Yingying, Lin, Marie Chia-Mi, Xu, Gaixia, Yong, Ken-Tye
• Other Authors: School of Electrical and Electronic Engineering
• Format: Article
• Language: English
• Published: 2018
• Subjects: Quantum Dots; RNA Interfering
• Online Access: https://hdl.handle.net/10356/86204; http://hdl.handle.net/10220/45381
• Institution: Nanyang Technological University

RNA interfering (RNAi) using short interfering RNA (siRNA) is becoming a promising approach for cancer gene therapy. However, owing to the lack of safe and efficient carriers, the application of RNAi for clinical use is still very limited. In this study, we have developed cadmium sulphoselenide/Zinc...