Polymorphism in Tmem132d regulates expression and anxiety-related behavior through binding of RNA polymerase II complex

Polymorphism in Tmem132d regulates expression and anxiety-related behavior through binding of RNA polymerase II complex

TMEM132D is a candidate gene, where risk genotypes have been associated with anxiety severity along with higher mRNA expression in the frontal cortex of panic disorder patients. Concurrently, in a high (HAB) and low (LAB) trait anxiety mouse model, Tmem132d was found to show increased expression in...

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Bibliographic Details
Main Authors: Naik, Roshan R., Sotnikov, Sergey V., Diepold, Rebekka P., Iurato, Stella, Markt, Patrick O., Bultmann, Andrea, Brehm, Nadine, Mattheus, Tobias, Lutz, Beat, Erhardt, Angelika, Binder, Elisabeth B., Schmidt, Ulrike, Holsboer, Florian, Landgraf, Rainer, Czibere, Ludwig
Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
Format: Article
Language:English
Published: 2018
Subjects:
Clinical Genetics
Genomics
Online Access:https://hdl.handle.net/10356/86287
http://hdl.handle.net/10220/45290
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Institution: Nanyang Technological University
Language: English

Internet

https://hdl.handle.net/10356/86287
http://hdl.handle.net/10220/45290

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