Comparative sphingolipidomics of disease-causing trypanosomatids reveal unique lifecycle- and taxonomy-specific lipid chemistries

• Main Authors: Guan, Xue Li, Mäser, Pascal
• Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
• Format: Article
• Language: English
• Published: 2017
• Subjects: Lipidomics; Metabolomics
• Online Access: https://hdl.handle.net/10356/86507; http://hdl.handle.net/10220/44085
• Institution: Nanyang Technological University

Trypanosomatids are parasitic protozoa which cause a spectrum of diseases, including trypanosomiasis and leishmaniasis, affecting millions of humans and animals worldwide. The surface of most protozoan parasites is heavily decorated with lipids and lipid-anchored molecules, forming protective barrie...