Non-Canonical G-quadruplexes cause the hCEB1 minisatellite instability in Saccharomyces cerevisiae

• Main Authors: Piazza, Aurèle, Cui, Xiaojie, Adrian, Michael, Samazan, Frédéric, Heddi, Brahim, Phan, Anh-Tuan, Nicolas, Alain G
• 其他作者: School of Physical and Mathematical Sciences
• 格式: Article
• 語言: English
• 出版: 2017
• 主題: Saccharomyces cerevisiae; G-quadruplexes (G4)
• 在線閱讀: https://hdl.handle.net/10356/86518; http://hdl.handle.net/10220/44054
• 機構: Nanyang Technological University

G-quadruplexes (G4) are polymorphic four-stranded structures formed by certain G-rich nucleic acids in vitro, but the sequence and structural features dictating their formation and function in vivo remains uncertain. Here we report a structure-function analysis of the complex hCEB1 G4-forming sequen...