Intraocular Pressure, Axial Length, and Refractive Changes after Phacoemulsification and Trabeculectomy for Open-Angle Glaucoma

Purpose. To compare changes in intraocular pressure (IOP), axial eye length (AEL), and refractive outcome in primary open-angle glaucoma patients undergoing cataract surgery and trabeculectomy in dependence of the sequence of surgeries. Materials and Methods. We retrospectively analysed 48 eyes. The...

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Main Authors: Popa-Cherecheanu, Alina, Iancu, Raluca Claudia, Schmetterer, Leopold, Pirvulescu, Ruxandra, Coviltir, Valeria
Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
Format: Article
Language:English
Published: 2017
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Online Access:https://hdl.handle.net/10356/86523
http://hdl.handle.net/10220/44050
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Institution: Nanyang Technological University
Language: English
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spelling sg-ntu-dr.10356-865232020-11-01T05:19:05Z Intraocular Pressure, Axial Length, and Refractive Changes after Phacoemulsification and Trabeculectomy for Open-Angle Glaucoma Popa-Cherecheanu, Alina Iancu, Raluca Claudia Schmetterer, Leopold Pirvulescu, Ruxandra Coviltir, Valeria Lee Kong Chian School of Medicine (LKCMedicine) Refractive Changes Open-Angle Glaucoma Purpose. To compare changes in intraocular pressure (IOP), axial eye length (AEL), and refractive outcome in primary open-angle glaucoma patients undergoing cataract surgery and trabeculectomy in dependence of the sequence of surgeries. Materials and Methods. We retrospectively analysed 48 eyes. The changes in refraction, intraocular pressure, and axial eye length were analysed after surgery. In group A (21 subjects), phacoemulsification was performed before trabeculectomy, and in group B (27 subjects), trabeculectomy was performed before phacoemulsification with a minimum time span between interventions of 6 months. Results. The reduction in IOP and the decrease in AEL after trabeculectomy were significant after 6 and 12 months postsurgery ( p<0.001 each). The decrease in AEL was 0.42 ± 0.11% at 6 months after surgery and 0.40 ± 0.13% after 12 months from surgery; this decrease in AEL was comparable between the groups. The refractive outcome was significantly different between the groups (group A: 0.35 ± 0.75 dpt, group B: −0.05 ± 0.36 dpt, p =0.018 ); in group A, trabeculectomy caused a hyperopic shift of 0.34 ± 0.44 dpt (p = 0.002) at 12 months postsurgery. Conclusion. IOP reduction after trabeculectomy causes AEL shortening. The effect on refractive outcome depends on the sequence of surgeries. Better refractive outcome is achieved if phacoemulsification is performed after trabeculectomy. Published version 2017-11-15T07:34:49Z 2019-12-06T16:23:55Z 2017-11-15T07:34:49Z 2019-12-06T16:23:55Z 2017 Journal Article Popa-Cherecheanu, A., Iancu, R. C., Schmetterer, L., Pirvulescu, R., & Coviltir, V. (2017). Intraocular Pressure, Axial Length, and Refractive Changes after Phacoemulsification and Trabeculectomy for Open-Angle Glaucoma. Journal of Ophthalmology, 2017, 1203269-. 2090-004X https://hdl.handle.net/10356/86523 http://hdl.handle.net/10220/44050 10.1155/2017/1203269 en Journal of Ophthalmology © 2017 Alina Popa-Cherecheanu et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. 6 p. application/pdf
institution Nanyang Technological University
building NTU Library
continent Asia
country Singapore
Singapore
content_provider NTU Library
collection DR-NTU
language English
topic Refractive Changes
Open-Angle Glaucoma
spellingShingle Refractive Changes
Open-Angle Glaucoma
Popa-Cherecheanu, Alina
Iancu, Raluca Claudia
Schmetterer, Leopold
Pirvulescu, Ruxandra
Coviltir, Valeria
Intraocular Pressure, Axial Length, and Refractive Changes after Phacoemulsification and Trabeculectomy for Open-Angle Glaucoma
description Purpose. To compare changes in intraocular pressure (IOP), axial eye length (AEL), and refractive outcome in primary open-angle glaucoma patients undergoing cataract surgery and trabeculectomy in dependence of the sequence of surgeries. Materials and Methods. We retrospectively analysed 48 eyes. The changes in refraction, intraocular pressure, and axial eye length were analysed after surgery. In group A (21 subjects), phacoemulsification was performed before trabeculectomy, and in group B (27 subjects), trabeculectomy was performed before phacoemulsification with a minimum time span between interventions of 6 months. Results. The reduction in IOP and the decrease in AEL after trabeculectomy were significant after 6 and 12 months postsurgery ( p<0.001 each). The decrease in AEL was 0.42 ± 0.11% at 6 months after surgery and 0.40 ± 0.13% after 12 months from surgery; this decrease in AEL was comparable between the groups. The refractive outcome was significantly different between the groups (group A: 0.35 ± 0.75 dpt, group B: −0.05 ± 0.36 dpt, p =0.018 ); in group A, trabeculectomy caused a hyperopic shift of 0.34 ± 0.44 dpt (p = 0.002) at 12 months postsurgery. Conclusion. IOP reduction after trabeculectomy causes AEL shortening. The effect on refractive outcome depends on the sequence of surgeries. Better refractive outcome is achieved if phacoemulsification is performed after trabeculectomy.
author2 Lee Kong Chian School of Medicine (LKCMedicine)
author_facet Lee Kong Chian School of Medicine (LKCMedicine)
Popa-Cherecheanu, Alina
Iancu, Raluca Claudia
Schmetterer, Leopold
Pirvulescu, Ruxandra
Coviltir, Valeria
format Article
author Popa-Cherecheanu, Alina
Iancu, Raluca Claudia
Schmetterer, Leopold
Pirvulescu, Ruxandra
Coviltir, Valeria
author_sort Popa-Cherecheanu, Alina
title Intraocular Pressure, Axial Length, and Refractive Changes after Phacoemulsification and Trabeculectomy for Open-Angle Glaucoma
title_short Intraocular Pressure, Axial Length, and Refractive Changes after Phacoemulsification and Trabeculectomy for Open-Angle Glaucoma
title_full Intraocular Pressure, Axial Length, and Refractive Changes after Phacoemulsification and Trabeculectomy for Open-Angle Glaucoma
title_fullStr Intraocular Pressure, Axial Length, and Refractive Changes after Phacoemulsification and Trabeculectomy for Open-Angle Glaucoma
title_full_unstemmed Intraocular Pressure, Axial Length, and Refractive Changes after Phacoemulsification and Trabeculectomy for Open-Angle Glaucoma
title_sort intraocular pressure, axial length, and refractive changes after phacoemulsification and trabeculectomy for open-angle glaucoma
publishDate 2017
url https://hdl.handle.net/10356/86523
http://hdl.handle.net/10220/44050
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