Metagenomic and metatranscriptomic analysis of saliva reveals disease-associated microbiota in patients with periodontitis and dental caries

• Main Authors: Drautz-Moses, Daniela Isabel, Schuster, Stephan Christoph, Belstrøm, Daniel, Constancias, Florentin, Liu, Yang, Yang, Liang, Kohli, Gurjeet Singh, Jakobsen, Tim Holm, Holmstrup, Palle, Givskov, Michael
• Other Authors: Singapore Centre for Environmental Life Sciences Engineering
• Format: Article
• Language: English
• Published: 2018
• Subjects: Metagenomic; Metatranscriptomics
• Online Access: https://hdl.handle.net/10356/86646; http://hdl.handle.net/10220/45339
• Institution: Nanyang Technological University

The taxonomic composition of the salivary microbiota has been reported to differentiate between oral health and disease. However, information on bacterial activity and gene expression of the salivary microbiota is limited. The purpose of this study was to perform metagenomic and metatranscriptomic c...