Value of soluble Urokinase plasminogen activator receptor over age as a biomarker of impaired myocardial relaxation

• Main Authors: Koh, Angela S., Velmurugan, Bhaarathy, Gao, Fei, Tan, Ru San, Wong, Jia-Ing, Teo, Louis L. Y., Keng, Bryan M. H., Chua, Serene J. M., Yuan, Jian-Min, Koh, Woon-Puay, Cheung, Christine
• Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
• Format: Article
• Language: English
• Published: 2018
• Subjects: Soluble Urokinase Plasminogen Activator Receptor; Biomarker
• Online Access: https://hdl.handle.net/10356/86663; http://hdl.handle.net/10220/45343
• Institution: Nanyang Technological University

Background: SuPAR is a biomarker that reflects the level of immune activation. As inflammation plays an important role in the ageing process of the cardiovascular system, we hypothesized that suPAR might be a useful predictive biomarker of the ageing heart. Methods: We performed conventional and tis...