The central element of the synaptonemal complex in mice is organized as a bilayered junction structure

• Main Authors: Hernández-Hernández, Abrahan, Masich, Sergej, Fukuda, Tomoyuki, Kouznetsova, Anna, Sandin, Sara, Daneholt, Bertil, Höög, Christer
• Other Authors: School of Biological Sciences
• Format: Article
• Language: English
• Published: 2017
• Subjects: Synaptonemal Complex; Meiosis
• Online Access: https://hdl.handle.net/10356/86678; http://hdl.handle.net/10220/44123
• Institution: Nanyang Technological University

The synaptonemal complex transiently stabilizes pairing interactions between homologous chromosomes during meiosis. Assembly of the synaptonemal complex is mediated through integration of opposing transverse filaments into a central element, a process that is poorly understood. We have, here, analyz...