Compact photoacoustic tomography system

Photoacoustic tomography (PAT) is a non-ionizing biomedical imaging modality which finds applications in brain imaging, tumor angiogenesis, monitoring of vascularization, breast cancer imaging, monitoring of oxygen saturation levels etc. Typical PAT systems uses Q-switched Nd:YAG laser light illumin...

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Main Authors: Kalva, Sandeep Kumar, Pramanik, Manojit
Other Authors: Oraevsky, Alexander A.
Format: Conference or Workshop Item
Language:English
Published: 2018
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Online Access:https://hdl.handle.net/10356/86899
http://hdl.handle.net/10220/44307
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Institution: Nanyang Technological University
Language: English
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spelling sg-ntu-dr.10356-868992023-12-29T06:44:06Z Compact photoacoustic tomography system Kalva, Sandeep Kumar Pramanik, Manojit Oraevsky, Alexander A. Wang, Lihong V. School of Chemical and Biomedical Engineering Proceedings of SPIE - Photons Plus Ultrasound: Imaging and Sensing 2017 Acoustic Reflector Photoacoustic Tomography Photoacoustic tomography (PAT) is a non-ionizing biomedical imaging modality which finds applications in brain imaging, tumor angiogenesis, monitoring of vascularization, breast cancer imaging, monitoring of oxygen saturation levels etc. Typical PAT systems uses Q-switched Nd:YAG laser light illumination, single element large ultrasound transducer (UST) as detector. By holding the UST in horizontal plane and moving it in a circular motion around the sample in full 2π radians photoacoustic data is collected and images are reconstructed. The horizontal positioning of the UST make the scanning radius large, leading to larger water tank and also increases the load on the motor that rotates the UST. To overcome this limitation, we present a compact photoacoustic tomographic (ComPAT) system. In this ComPAT system, instead of holding the UST in horizontal plane, it is held in vertical plane and the photoacoustic waves generated at the sample are detected by the UST after it is reflected at 45° by an acoustic reflector attached to the transducer body. With this we can reduce the water tank size and load on the motor, thus overall PAT system size can be reduced. Here we show that with the ComPAT system nearly similar PA images (phantom and in vivo data) can be obtained as that of the existing PAT systems using both flat and cylindrically focused transducers. NMRC (Natl Medical Research Council, S’pore) MOH (Min. of Health, S’pore) Published version 2018-01-10T09:02:10Z 2019-12-06T16:31:13Z 2018-01-10T09:02:10Z 2019-12-06T16:31:13Z 2017 Conference Paper Kalva, S. K., & Pramanik, M. (2017). Compact photoacoustic tomography system. Proceedings of SPIE - Photons Plus Ultrasound: Imaging and Sensing 2017, 10064, 100643X-. https://hdl.handle.net/10356/86899 http://hdl.handle.net/10220/44307 10.1117/12.2250493 en © 2017 Society of Photo-Optical Instrumentation Engineers (SPIE). This paper was published in Proceedings of SPIE - Photons Plus Ultrasound: Imaging and Sensing 2017 and is made available as an electronic reprint (preprint) with permission of Society of Photo-Optical Instrumentation Engineers (SPIE). The published version is available at: [http://dx.doi.org/10.1117/12.2250493]. One print or electronic copy may be made for personal use only. Systematic or multiple reproduction, distribution to multiple locations via electronic or other means, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper is prohibited and is subject to penalties under law. 6 p. application/pdf
institution Nanyang Technological University
building NTU Library
continent Asia
country Singapore
Singapore
content_provider NTU Library
collection DR-NTU
language English
topic Acoustic Reflector
Photoacoustic Tomography
spellingShingle Acoustic Reflector
Photoacoustic Tomography
Kalva, Sandeep Kumar
Pramanik, Manojit
Compact photoacoustic tomography system
description Photoacoustic tomography (PAT) is a non-ionizing biomedical imaging modality which finds applications in brain imaging, tumor angiogenesis, monitoring of vascularization, breast cancer imaging, monitoring of oxygen saturation levels etc. Typical PAT systems uses Q-switched Nd:YAG laser light illumination, single element large ultrasound transducer (UST) as detector. By holding the UST in horizontal plane and moving it in a circular motion around the sample in full 2π radians photoacoustic data is collected and images are reconstructed. The horizontal positioning of the UST make the scanning radius large, leading to larger water tank and also increases the load on the motor that rotates the UST. To overcome this limitation, we present a compact photoacoustic tomographic (ComPAT) system. In this ComPAT system, instead of holding the UST in horizontal plane, it is held in vertical plane and the photoacoustic waves generated at the sample are detected by the UST after it is reflected at 45° by an acoustic reflector attached to the transducer body. With this we can reduce the water tank size and load on the motor, thus overall PAT system size can be reduced. Here we show that with the ComPAT system nearly similar PA images (phantom and in vivo data) can be obtained as that of the existing PAT systems using both flat and cylindrically focused transducers.
author2 Oraevsky, Alexander A.
author_facet Oraevsky, Alexander A.
Kalva, Sandeep Kumar
Pramanik, Manojit
format Conference or Workshop Item
author Kalva, Sandeep Kumar
Pramanik, Manojit
author_sort Kalva, Sandeep Kumar
title Compact photoacoustic tomography system
title_short Compact photoacoustic tomography system
title_full Compact photoacoustic tomography system
title_fullStr Compact photoacoustic tomography system
title_full_unstemmed Compact photoacoustic tomography system
title_sort compact photoacoustic tomography system
publishDate 2018
url https://hdl.handle.net/10356/86899
http://hdl.handle.net/10220/44307
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